منابع مشابه
Validating Animal Models
This paper responds to a recent challenge for the validity of extrapolation of neurobiological knowledge from laboratory animals to humans. According to this challenge, experimental neurobiology, and thus neuroscience, is in a state of crisis because the knowledge produced in different laboratories hardly generalizes from one laboratory to another. Presumably, this is so because neurobiological...
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We summarize some of the most frequenthly used rodent animal models of temporal lobe epileps and the impact of chemoconvulsants on them. Temporal lobe epilepsy is the most common epilepsy in humans in which seizures spread to the neighboring cortiase and hippocampal neuron loss and other neuropathological take place. Temporal lobe epilepsy and the other form of epilepsy cannot acquired in chini...
متن کاملValidating Simulation Models
This paper discusses aspects of validating simulation models designed to describe, explain and predict realworld phenomena. It starts with a short review of arguments used in the simsoc mailing list discussion on theory, simulation and explanation a few months ago, deals with the use of quantitative and qualitative computational models to make quantitative and qualitative predictions or rather ...
متن کاملValidating Simulation Models
This paper provides a framework for discussing the empirical validation of computer simulation models of market phenomena. It considers first a simulation model of a market of competing coffee brands to ask some questions about the purposes and practices of simulation modeling. It defines functional complexity and derives measures of this for Schelling’s Segregation model. It refers to the Ener...
متن کاملValidating Computational Models
The use of computational models in the social sciences has grown quickly in the past decade. For many these models represent a bewildering and possibly intimidating approach to examining data and developing social and organizational theory. Few researchers have had courses or personal experience in the development and building of computational models and even fewer have an understanding of how ...
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ژورنال
عنوان ژورنال: THEORIA. An International Journal for Theory, History and Foundations of Science
سال: 2015
ISSN: 2171-679X,0495-4548
DOI: 10.1387/theoria.12761